Peer-Reviewed Research
Dr. Claire Sterling, Ph.D., Prof. Raymond K. Vance, Dr. Yemi Adebayo, Ph.D.
Background: The integration of Large Language Model (LLM) conversational tutors into higher education STEM classrooms risks creating cognitive offloading and superficial learning. We evaluate an adaptive Socratic GenAI tutoring system across 850 undergraduate engineering students…
Peer-Reviewed Research
Prof. Beatrice Laurent, Ph.D., Dr. Haoran Zhao, Dr. Carlos Mendez, Ph.D.
Background: Tracking the conceptual evolution of socio-political keywords across the Enlightenment requires scaling beyond close reading. Utilizing temporal vector-space word embeddings (Diachronic Word2Vec and BERT) across 120,000 digitized historical texts, we trace the semantic divergence…
Peer-Reviewed Research
Prof. Sean O'Connor, Ph.D., Dr. Elena Rostova, Ph.D., Prof. Douglas Sterling, Ph.D.
Background: The decommissioning of heavy industrial infrastructure in former manufacturing heartlands leaves behind fraught landscapes of toxic contamination, economic dispossession, and contested working-class memory. We investigate the spatial politics of industrial heritage conversion across the…
Peer-Reviewed Research
Prof. Julian Thorne, Ph.D., Dr. Mei-Ling Wu, Ph.D., Prof. Alberto Rossi, Ph.D.
Background: How multinational corporations recalibrate financial leverage in response to acute macroeconomic liquidity shocks remains a contentious issue in corporate finance. Using a fractional panel GMM estimator across 4,200 firms from 28 OECD economies over…
Peer-Reviewed Research
Prof. Alexander Vance, M.D., Ph.D., Dr. Elena Rostova, Ph.D., Dr. Kenji Takahashi, M.D.
Background: Sodium-glucose cotransporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists confer distinct organoprotective benefits in type 2 diabetes mellitus (T2DM). In this prospective cohort of 18,450 patients over 42.6 months, SGLT2 inhibitors demonstrated superior…
Peer-Reviewed Research
Dr. Beatrice Dupont, Ph.D., Prof. Magnus Lindholm, Dr. Fiona Gallagher, Ph.D.
Background: As sustainable finance expands, financial institutions increasingly link lending terms to environmental, social, and governance (ESG) metrics. We examine whether banks penalize ESG decoupling—the divergence between symbolic green rhetoric and substantive operational performance—across 2,850…
Peer-Reviewed Research
Dr. Marcus Thorne, M.D., Dr. Sophia Chen, Ph.D., Prof. David K. Miller, FRCPath
Background: Third-generation EGFR tyrosine kinase inhibitors, notably osimertinib, constitute first-line therapy for EGFR-mutant advanced NSCLC. We demonstrate that longitudinal circulating tumor DNA (ctDNA) tracking via ultra-deep NGS detects emerging resistance mutations (C797S, MET amplification) a…
Peer-Reviewed Research
Dr. Astrid Lindholm, M.D., Ph.D., Dr. Rajesh Varma, M.D., Prof. Charlotte Dubois, Ph.D.
Background: Early identification of preclinical Alzheimer's disease pathology remains essential for disease-modifying therapies. In this prospective 5-year multicenter study of 1,420 cognitively unimpaired elderly individuals, baseline plasma p-tau217 demonstrated exceptional diagnostic accuracy (AUC 0.94) for…
Peer-Reviewed Research
Prof. Roberto Moretti, M.D., Dr. Amina Al-Mansoor, Ph.D., Dr. Christian Becker, M.D.
Background: Transfusion-dependent beta-thalassemia (TDT) requires lifelong red blood cell transfusions and iron chelation. Non-viral electroporation of autologous CD34+ hematopoietic stem cells targeting the erythroid-specific BCL11A enhancer via Cas9 ribonucleoproteins demonstrated sustained transfusion independence in 92.8%…
Peer-Reviewed Research
Dr. Sarah Jenkins, Ph.D., Prof. Aris Thorne, M.D., Dr. Natalia Gomez, Ph.D.
Background: Candida auris is an emerging multidrug-resistant fungal pathogen responsible for protracted outbreaks in healthcare facilities. Whole-genome sequencing of 240 clinical and environmental isolates from 8 intensive care units mapped clonal transmission dynamics and revealed…
